Introduction to Bioinformatics: CMSC54610-1, Spring quarter 2006.

Lecture 8: Genomics and Gene Recognition

• GC content in eukaryotics
  • CpG islands
  • density of CpG indicates coding region
  • Cytosine methylation
    • makes C more like the others (12->15 atoms)
    • oxidative deamination changes meth-C to T
  • Cromatin and histone proteins
    • epigenetic factor

Back to Lecture 8: Genomics and Gene Recognition