Introduction to Bioinformatics: CMSC54610-1, Spring quarter 2006.

Lecture 9: 24 May 2006

We are meeting today in Ry 277

• GC content in Eukaryotic Genomes
• L1 and Alu ( repeat ) sequences
• DNA archeology
• SAGE and GLGI
• bioinfo payoff: fixing the record, cf.
  • Correct Identification of Genes from Serial Analysis of Gene Expression Tag Sequences
• relation to matching contigs in shotgun sequencing
• Data mining and quantum mechanics

In preparation for next week, please read

• A new dynamic Bayesian network (DBN) approach for identifying gene regulatory networks from time course microarray data and
• Modelling Gene Expression Data using Dynamic Bayesian Networks