This course will explore the digital nature of biology at the molecular scale. We will examine the digital nature of protein interactions modulated by the hydrophobic effect.
The course will explore the connections among the following well known but seemingly contradictory facts:
The course will describe the use of datamining to understand the biophysics of proteins, and we will review the derivation of basic models for dielectrics. We will also discuss some changes at the quantum level caused by the large-scale hydrophobic and electronic environment. Implications for protein folding models will be discussed.
No particular background will be assumed. All prerequisites will be provided in the class. We will explore issues in computer science, applied mathematics, physical chemistry and biomedical applications. It is hoped that people from different disciplines will participate.
Notes for the course will be distributed and students will read primary journal articles.
Some Journals for the course.